A woman’s egg quality declines with age. Even with a high egg reserve, some women are unable to conceive. Growth factors may revitalize existing eggs and improve their quality – permitting conception to occur.
Egg Reserve and Quality
A woman is born with a fixed number of eggs in her ovaries. This lifetime supply is not replenished by the spontaneous growth of new eggs during her reproductive years. There are several methods of testing the reserve (supply or quantity) of eggs remaining a woman’s ovaries.
As a woman ages, her ovaries are unable to produce the hormones that stimulate egg follicles to develop and make them reach a viable stage of development. To determine whether a woman can conceive with her existing egg supply, age is a determining consideration.
A woman’s supply of eggs will be used up somewhere between 25 and 55 years of age. Poor genetic quality of eggs results in infertility, even when there are many eggs remaining in a woman’s ovarian reserve.
A woman’s egg quantity and quality can be:
- Average for her age
- Better than average
- Worse than average
- A 45-year old woman can have good egg quality – although this is rare
- A 25-year old woman can have very poor egg quality and be infertile as a result
A woman in her 40s may still be able to ovulate, but her healthy eggs may have been depleted and those remaining are of a poor quality, potentially leading to an increased chance of an abnormal pregnancy.
Ovarian Reserve Tests
A woman’s ovarian reserve determines the capacity of her ovary to provide egg cells that are capable of fertilization resulting in a healthy and successful pregnancy. The following procedures are ovarian reserve tests commonly used to determine a woman’s present egg supply.
- Antral Follicle Count Test
- Day 3 FSH and E2 Test
- Clomiphene Challenge Test
- AMH Test
Antral Follicle Count Test
Counting the number of 2-9mm diameter antral follicles that can be seen with transvaginal ultrasound can estimate a woman’s ovarian reserve.
Day 3 FSH and E2 Test
Follicle Stimulating Hormone (FSH) and Estradiol Test (E2) measures the baseline of a woman’s FSH on day 3 of her menstrual cycle.
This test can indicate that a woman is close to menopause and has a low ovarian reserve. If a woman’s Day 3 FSH is elevated, her ovarian reserve is low to the point of being infertile.
Clomiphene Challenge Test
A clomiphene challenge test is a test that can discover cases of poor ovarian reserve that are still showing a normal day 3 FSH.
The Anti-Mullerian Hormone test checks the blood levels of the hormone AMH to evaluate a woman’s ovarian reserve.
Ovarian Rejuvenation Therapy
Ovarian Rejuvenation Therapy is an innovative Assisted Reproductive Technology (ART) procedure used to wake up and coax a woman’s nonfunctioning ovaries into producing viable eggs. Dr. Hugh Melnick is one of a handful of fertility doctors offering ovarian rejuvenation therapy.
Ovarian Rejuvenation Therapy involves the injection of a woman’s Platelet Rich Plasma (PRP) directly into her ovaries. The expected clinical result from this procedure is to induce Growth Factors to help the ovaries functioning again – even post-menopause.
Results of Ovarian Rejuvenation Therapy
A total of 42 women having undergone Ovarian Rejuvenation Therapy were contacted for a follow-up interview by the Doctor.
- 21 women (50%) had resumed menstruation
- 9 women (21.4%) reported cyclic symptoms of menstruation without bleeding
- Decrease in hot flashes
- Increased vaginal lubrication
- Increase in sexual drive
- 8 women (19%) reported no menstruation and no improvement in menopausal symptoms
- 3 women conceived naturally (7% live birth rate)
- 1 woman suffered a miscarriage
Fertility Doctor Specializing in Ovarian Rejuvenation Therapy
Dr. Melnick has been successfully treating infertile couples since 1976. The Doctor has accomplished over 10,000 successful IVF procedures – using known eggs and donor eggs. In 1983, Dr. Melnick founded Advanced Fertility Services in NYC – the tri-state area’s first private, freestanding IVF center – located in Manhattan’s Upper East Side.
Other stellar attributes of Dr. Melnick:
- Pioneering doctor of preserving a woman’s future fertility through the world class Oocyte Preservation Program
- Renowned publisher of numerous scientific research articles in prominent medical journals and medical textbook contributions
- Acclaimed author of The Pregnancy Prescription – a prestigious book written for those coping with the challenges of infertility, including information on how best to overcome infertility
Read the Doctor’s contribution to the American Journal of Obstetrics & Gynecology about subclinical hypothyroidism and its effect on a woman’s fertility.
How to Know if You’re a Candidate
Your initial consultation to find out if you are a candidate for Ovarian Rejuvenation Therapy can be conducted with the Doctor via telephone, Skype or FaceTime.
- Print your intake form by clicking here
- Print your information and consent form by clicking here
- Complete, scan and email these forms to email@example.com.
Read More About Ovarian Rejuvenation
It is important to work with a fertility specialist who has the clinical experience to design an infertility treatment plan meeting your personal needs.
To read more about Ovarian Rejuvenation Therapy, check out the Doctor’s Blog here.
Schedule your initial consultation with Dr. Hugh Melnick at Advanced Fertility Services by calling 212.369.8700 – or – clicking the icon below.