WHAT IS OVARIAN REJUVENATION WITH PLATELET RICH PLASMA (PRP)?
Ovarian rejuvenation may restore fertility and stimulate natural hormonal production in some women who are unable to conceive or who suffer with symptoms associated with hormone deficiency. In Ovarian Rejuvenation, a preparation of a woman’s own blood cells, called Platelet Rich Plasma (PRP), is injected into her ovaries to stimulate new cellular growth in an attempt to restore fertility and ovarian hormone production. Ovarian rejuvenation is a new application of Platelet Rich Plasma (PRP) therapy, which is used in Dermatology, Plastic Surgery, Sports Medicine, Orthopedics, Gynecology and Dentistry.
HOW DOES PRP (PLATELET RICH PLASMA) THERAPY WORK?
PRP therapy is based upon our knowledge of the way in which the body naturally heals itself in repairing damaged tissues. Platelet cells are attracted to the site of an injury and release a group of substances, known as Growth Factors, each of which makes a unique biologic contribution to the complex process by which the body heals itself.
As part of the healing process, certain Growth Factors stimulate the growth of new cells from Stem Cells which ultimately form new blood vessels, connective tissue, and nerves to replace the damaged tissues in the area of injury.
The current belief is that Growth Factors derived from platelets may have a similar regenerative effect on ovarian tissue as it does in the natural reparative process of the human body. By introducing PRP into the ovaries, new cellular growth may be stimulated to restore fertility and hormonal function in certain women.
HOW ARE NEW EGGS AND HORMONE PRODUCING CELLS FORMED?
There is evidence which indicates that Stem Cells, found in the ovaries, can be induced to morph into new eggs and hormone producing cells by the injection of autologous (the patient’s own) Platelet Rich Plasma into the ovaries. The occurrence of viable pregnancies in irreversibly infertile women after intra-ovarian PRP injection demonstrates that fertility and ovarian hormone production can be restored in some hopeless cases.
Thus far, two irreversibly infertile women have achieved viable pregnancies naturally after PRP treatment in our clinic. Pregnancies after PRP therapy have also been reported in other clinics. In our clinic, two women have conceived naturally (without IVF) and given birth after PRP therapy. Both women, who had multiple failed IVF treatment cycles, conceived between 8 and 20 weeks after PRP injection.