How Ovarian Reserve Tests Work

How Ovarian Reserve Tests Work

As a woman ages, her ovaries don’t produce the hormones required to stimulate her egg follicles into a viable stage of development to be fertilized. A woman’s egg quality declines with age. Growth factors may revitalize existing eggs and improve their quality – permitting fertilization to occur.

Ovarian Reserve Tests

A woman’s supply of eggs will be used up somewhere between 25 and 55 years of age. Poor genetic quality of eggs results in infertility, even when there are many eggs remaining in a woman’s ovarian reserve.

A woman’s egg quantity and quality can be:

  • Average for her age
  • Better than average
  • Worse than average

A woman’s ovarian reserve determines the capacity of her ovary to provide egg cells that are capable of fertilization resulting in a healthy and successful pregnancy. The following procedures are ovarian reserve tests commonly used to determine a woman’s present egg supply.

  • Antral Follicle Count Test
  • Day 3 FSH and E2 Test
  • Clomiphene Challenge Test
  • AMH Test

Antral Follicle Count Test

Counting the number of 2-9mm diameter antral follicles that can be seen with transvaginal ultrasound can estimate a woman’s ovarian reserve.

Day 3 FSH and E2 Test

Follicle Stimulating Hormone (FSH) and Estradiol Test (E2) measures the baseline of a woman’s FSH on day 3 of her menstrual cycle.

This test can indicate that a woman is close to menopause and has a low ovarian reserve. If a woman’s Day 3 FSH is elevated, her ovarian reserve is low to the point of being infertile.

Clomiphene Challenge Test

A clomiphene challenge test is a test that can discover cases of poor ovarian reserve that are still showing a normal day 3 FSH.

AMH Test

The Anti-Mullerian Hormone test checks the blood levels of the hormone AMH to evaluate a woman’s ovarian reserve.

Ovarian Rejuvenation Therapy

Ovarian Rejuvenation Therapy is an innovative Assisted Reproductive Technology (ART) procedure used to wake up and coax a woman’s nonfunctioning ovaries into producing viable eggs. Dr. Hugh Melnick is one of a handful of fertility doctors offering ovarian rejuvenation therapy.

Ovarian Rejuvenation Therapy involves the injection of a woman’s Platelet Rich Plasma (PRP) directly into her ovaries. The expected clinical result from this procedure is to induce Growth Factors to help the ovaries functioning again – even post-menopause.

Results of Ovarian Rejuvenation Therapy

A total of 42 women having undergone Ovarian Rejuvenation Therapy were contacted for a follow-up interview by the Doctor.

  • 21 women (50%) had resumed menstruation
  • 9 women (21.4%) reported cyclic symptoms of menstruation without bleeding
  • Decrease in hot flashes
  • Increased vaginal lubrication
  • Increase in sexual drive
  • 8 women (19%) reported no menstruation and no improvement in menopausal symptoms
  • 3 women conceived naturally (7% live birth rate)
  • 1 woman suffered a miscarriage

Ovarian Rejuvenation Therapy Expertise

Your initial consultation to find out if you are a candidate for Ovarian Rejuvenation Therapy can be conducted with the Doctor via telephone, Skype or FaceTime.

Your initial consultation to find out if you are a candidate for Ovarian Rejuvenation Therapy can be conducted with the Doctor via telephone, Skype or FaceTime.

To read more about Ovarian Rejuvenation Therapy, check out the Doctor’s Blog here.

Schedule your initial consultation with Dr. Hugh Melnick at Advanced Fertility Services by calling 212.369.8700 – or – clicking the icon below.

Speak to Dr. Melnick