women were contacted for a follow up interview after intraovarian platelet rich plasma injection.
women resumed menstruation (50%).
women reported cyclic symptoms of menstruation without bleeding, decrease in hot flashes, increased vaginal lubrication or increase in sexual drive (21.4%).
women reported no menstruation and no improvement in menopausal symptoms (19%).
2 LIVE BIRTHS, CONCEIVED NATURALLY, AND 1 EARLY MISCARRIAGE (7% LIVE BIRTH RATE).
M.C. had a 5 year history of attempted conception. All fertility diagnostic tests were normal prior to multiple cycles of treatment with high dose ovarian stimulation and intrauterine insemination, which failed to produce a pregnancy. Multiple cycles of in vitro fertilization were unsuccessful in producing a viable pregnancy. The embryos produced were consistently of poor quality and she was diagnosed with age related infertility due to poor egg quality. The use of donor oocytes was recommended, but was not an option for her because of her religious beliefs. She subsequently elected to undergo an ovarian rejuvenation with platelet rich plasma injected into her ovaries, in the hope that it would have a positive effect on her egg quality. She was 43 years old when she conceived naturally, 5 months after intra ovarian platelet rich plasma injection, and delivered a healthy baby boy.
L. P. was a 41 year old woman who had been trying to conceive for two years. She was missing periods, had experienced typical symptoms of menopause and had elevated FSH levels. Prior attempts at IVF failed to produce viable eggs. She had a deep desire to have a baby, but the use of donated eggs was not acceptable method to achieve pregnancy. She became pregnant three months after intra ovarian platelet rich plasma therapy and is due to deliver in January, 2018.
Case # 3
H.C. was a 32 year old lady with premature menopause at the age of 30. She had two light periods after after platelet rich plasma injection, after which she a very early biochemical pregnancy (miscarriage). Unfortunately, she was lost to follow up, so we are not able to report whether she continued to menstruate or whether subsequent conception occurred.