A woman’s ovarian reserve determines her ability to achieve a healthy and successful pregnancy. As a woman ages, her ovaries are unable to produce key fertility hormones. How is a woman’s ovarian reserve tested?
Ovarian Reserve Tests
The following procedures are ovarian reserve tests commonly used to determine a woman’s present egg supply.
- Antral Follicle Count Test
- Day 3 FSH and E2 Test
- Clomiphene Challenge Test
- AMH Test
Antral Follicle Count Test
Counting the number of 2-9mm diameter antral follicles that can be seen with transvaginal ultrasound can estimate a woman’s ovarian reserve.
Day 3 FSH and E2 Test
Follicle Stimulating Hormone (FSH) and Estradiol Test (E2) measures the baseline of a woman’s FSH on day 3 of her menstrual cycle.
This test can indicate that a woman is close to menopause and has a low ovarian reserve. If a woman’s Day 3 FSH is elevated, her ovarian reserve is low to the point of being infertile.
Clomiphene Challenge Test
A clomiphene challenge test is a test that can discover cases of poor ovarian reserve that are still showing a normal day 3 FSH.
The Anti-Mullerian Hormone test checks the blood levels of the hormone AMH to evaluate a woman’s ovarian reserve.
Quality Egg Reserve
A woman is born with a fixed number of eggs in her ovaries. This lifetime supply is not replenished by the spontaneous growth of new eggs during her prime reproductive years. There are several successful testing methods to determine a woman’s remaining egg reserve – her supply and quantity of eggs in the ovaries.
Egg quality declines with the natural maternal aging process. Even with a high egg reserve, some women are unable to conceive. Growth factors may revitalize existing eggs and improve their quality – permitting conception to occur. A woman’s supply of eggs will be used up somewhere between 25 and 55 years of age. Poor genetic quality of eggs results in infertility, even when there are many eggs remaining in a woman’s ovarian reserve.
A woman’s egg quantity and quality can be:
- Average for her age
- Better than average
- Worse than average
- A 45-year old woman can have good egg quality – although this is rare
- A 25-year old woman can have very poor egg quality and be infertile as a result
A woman in her 40s may still be able to ovulate, but her healthy eggs may have been depleted and those remaining are of a poor quality, potentially leading to an increased chance of an abnormal pregnancy.
Ovarian Rejuvenation Therapy
Ovarian Rejuvenation Therapy is an innovative Assisted Reproductive Technology (ART) procedure used to wake up and coax a woman’s nonfunctioning ovaries into producing viable eggs. Dr. Hugh Melnick is one of a handful of fertility doctors offering ovarian rejuvenation therapy.
Ovarian Rejuvenation Therapy involves the injection of a woman’s Platelet Rich Plasma (PRP) directly into her ovaries. The expected clinical result from this procedure is to induce Growth Factors to help the ovaries functioning again – even post-menopause.
Results of Ovarian Rejuvenation Therapy
A total of 42 women having undergone Ovarian Rejuvenation Therapy were contacted for a follow-up interview by the Doctor.
- 21 women (50%) had resumed menstruation
- 9 women (21.4%) reported cyclic symptoms of menstruation without bleeding
- Decrease in hot flashes
- Increased vaginal lubrication
- Increase in sexual drive
- 8 women (19%) reported no menstruation and no improvement in menopausal symptoms
- 3 women conceived naturally (7% live birth rate)
- 1 woman suffered a miscarriage
Fertility Doctor Specializing in Ovarian Rejuvenation Therapy
Your initial consultation for Ovarian Rejuvenation Therapy can be conducted with the Doctor via telephone, Skype or FaceTime.
- Print your intake form by clicking here
- Print your information and consent form by clicking here
- Complete, scan and email these forms to firstname.lastname@example.org.
To read more about Ovarian Rejuvenation Therapy, check out the Doctor’s Blog here.
Schedule your initial consultation with Dr. Hugh Melnick at Advanced Fertility Services by calling 212.369.8700 – or – clicking the icon below.